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. 2022 Nov 23;13:7195. doi: 10.1038/s41467-022-34912-3

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© The Author(s) 2022

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Fig. 7 — The interactions with Y91 and Y471 are shown with dashed lines. They are involved in deprotonating 4-n-propylguaiacol (Fig. 1). The covalent and non-covalent substrates found in the structure of the S394V-EUGO5X mutant are shown in magenta and green, respectively. The substrate bound to the D151E/S394V/Q425S-EUGO5X mutant (PROGO) is shown in cyan. The side chains of the S394V-EUGO5X mutant are represented in green, with a darker green used for the subunit bearing the covalent adduct. The side chains of D151E/S394V/Q425S-EUGO5X are represented in light blue.