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. 2022 Nov 10;9:1051637. doi: 10.3389/fnut.2022.1051637

Table 6.

Characteristics of metabolic parameters according to gender and hansik intake defined by the Kdiet-index score and their associations.

Men (n = 20,293) Women (n = 38,408) Total
Low-hansik (n = 6,271) High-hansik (n = 14,022) Adjusted ORs and 95% CI Low-hansik (n = 7,728) High-hansik (n = 30,680) Adjusted ORs and 95% CI Adjusted ORs and 95% CI
MetS (%)1 1,084 (17.3) 2,514 (18.0) 0.923 (0.843–1.010) 888 (11.5) 3,814 (12.4) 0.876 (0.799–0.961) 0.874 (0.820–0.932)
BMI (mg/kg2)2 24.6 ± 0.04a 24.4 ± 0.03b 0.926 (0.863–0.992) 23.6 ± 0.04c 23.6 ± 0.02c***+++## 0.886 (0.830–0.946) 0.888 (0.847–0.931)
Waist (cm)3 86.0 ± 0.11a 85.4 ± 0.07b 0.911 (0.842–0.985) 78.0 ± 0.10c 78.1 ± 0.05c***++### 0.886 (0.830–0.946) 0.909 (0.861–0.961)
SMI4 7.14 ± 0.01a 7.18 ± 0.01a 1.912 (1.731–2.113) 6.11 ± 0.01b 6.12 ± 0.01b*** 1.673 (1.530–1.828) 1.759 (1.646–1.879)
Fat mass (%)5 23.2 ± 0.07b 23.0 ± 0.04c 0.899 (0.809–0.999) 30.7 ± 0.07a 30.6 ± 0.03a***+++ 0.866 (0.786–0.955) 0.877 (0.816–0.942)
Serum glucose (mg/dL)6 98.6 ± 0.42a 98.2 ± 0.27a 1.036 (0.918–1.169) 94.0 ± 0.41b 93.6 ± 0.18b*** 0.897 (0.769–1.047) 0.968 (0.880–1.065)
HbA1c (%)7 5.72 ± 0.02 5.72 ± 0.01 1.397 (1.121–1.740) 5.71 ± 0.02 5.71 ± 0.01 1.141 (0.885–1.472) 1.214 (0.948–1.500)
Insulin resistance8 700 (11.2) 1,612 (11.5) 0.967 (0.831–1.125) 419 (5.42) 1,873 (6.10) 0.866 (0.711–1.056) 0.917 (0.813–1.034)
Serum total cholesterol9 195 ± 0.77b 189 ± 0.52c 0.964 (0.855–1.086) 200 ± 0.74a 201 ± 0.35a***+++### 0.963 (0.865–1.071) 0.937 (0.866–1.014)
Serum HDL10 49.3 ± 0.28b 49.3 ± 0.19b 0.933 (0.826–1.053) 57.0 ± 0.27a 57.3 ± 0.13a***++ 1.103 (1.001–1.215) 1.039 (0.963–1.120)
Serum LDL11 117 ± 0.71b 113 ± 0.47c 0.978 (0.850–1.125) 121 ± 0.68a 120 ± 0.32a***+++### 0.943 (0.834–1.066) 0.935 (0.854–1.025)
Serum TG12 141 ± 1.77a 134 ± 1.18b 0.990 (0.899–1.090) 114 ± 1.71c 115 ± 0.80c***+## 0.970 (0.870–1.083) 0.955 (0.889–1.026)
SBP (mmHg)13 127 ± 0.31a 125 ± 0.20b 0.905 (0.823–0.996) 121 ± 0.30c 121 ± 0.14c***+## 1.031 (0.930–1.142) 0.947 (0.883–1.015)
DBP (mmHg)14 79.2 ± 0.21a 78.2 ± 0.14b 0.859 (0.750–0.984) 74.1 ± 0.20c 74.2 ± 0.09c***++### 0.864 (0.729–1.023) 0.849 (0.765–0.944)
Serum hs–CRP15 0.16 ± 0.01a 0.14 ± 0.01a 0.832 (0.592–1.169) 0.13 ± 0.01ab 0.13 ± 0.004b* 0.903 (0.585–1.393) 0.848 (0.650–1.106)
GFR16 81.8 ± 0.33c 84.0 ± 0.22b 1.363 (1.204–1.543) 84.1 ± 0.32b 87.3 ± 0.45a***+++### 1.784 (1.572–2.025) 1.535 (1.405–1.678)
Serum AST (U/L)17 25.5 ± 0.25a 24.9 ± 0.17b 0.856 (0.698–1.050) 23.1 ± 0.24c 22.9 ± 0.11c***+ 0.991 (0.763–1.289) 0.897 (0.765–1.053)
Serum ALT(U/L)18 26.7 ± 0.37a 25.7 ± 0.25a 1.010 (0.891–1.144) 19.7 ± 0.36b 19.8 ± 0.17b***# 0.956 (0.801–1.141) 0.969 (0.875–1.072)

The score of each component meeting the criteria was 1. If not, the score was 0. The Kdiet-index score was calculated by summing the scores of each component in the hansik definition. High- and low-hansik intake indicated the Kdiet-index scores ≥8 or <8, respectively. A Higher Kdiet-index score indicated a higher hansik intake. ORs, Odds ratio; CI, confidence intervals. Covariates for adjustment included age, energy intake, body mass index (BMI), residence area, education, income, alcohol intake, smoking status, and physical activity. The cutoff points of hansik intake for logistic regression were as following:

1

Metabolic syndrome (MetS) criteria;

2

<25 kg/m2 for body mass index (BMI);

3

< 90 cm for men and 85 cm for women waist circumferences;

4

<29.0 % for men and 22.8 % for women in skeletal muscle index (SMI; defined as appendicular skeletal muscle mass/height);

5

< 25% for men and 30% for women for fat mass;

6

<126 ml/dL fasting serum glucose plus diabetic drug intake;

7

<6.5% hbA1c plus diabetic drug intake;

8

<2.54 HOMA-IR;

9

<230 mg/dL serum total cholesterol concentrations;

10

<40 mg/dL for men and 50 mg/dL for women serum HDL cholesterol;

11

<160 mg/dL serum LDL cholesterol concentrations;

12

<150 mg/dL serum triglyceride concentrations;

13

<140 mmHg systolic blood pressure (SBP);

14

diastolic blood pressure (DBP) <90 mmHg plus hypertension medication;

15

<0.5 mg/dL serum high sensitive-C-reactive protein (hs-CRP) concentrations;

16

Estimated glomerular filtration rate (GFR) <60;

17

<40 U/L Aspartate aminotransferase;

18

<35 U/L Alanine aminotransferase.

*

Significant differences by genders at P < 0.05,

***

P < 0.001.

+

Significant differences by hansik intake at P < 0.05, at

++

P < 0.01,

+++

P < 0.001.

#

Significant interaction between genders and hansik intake at P < 0.05, at

##

P < 0.01,

###

P < 0.001.

a, b, c

Different superscripts on the values indicated significant differences among the groups in Tukey's test at P < 0.05.