Table 2.
Details of exosome-derived miRNAs targeting the TME to regulate ovarian cancer.
| miRNA | Target genes | Related hallmark | Expression | reference |
|---|---|---|---|---|
| miR-940 | CD163/CD206 | Proliferation/Migtation | Promote | (108) |
| miR-124-3p | BAX/CASP9/CASP3 | Proliferation | Inhibit | (109) |
| miR-205 | VEGFA | Proliferation/Migtation | Promote | (110) |
| miR-6126 | Integrin-β1 | Proliferation | Inhibit | (111) |
| miR-940 | SRC | Proliferation | Inhibit | (112) |
| miR-200 | CD63/CD9 | Migtation | Promote | (113) |
| miR-99a-5p | HPMCs | Migtation | Promote | (114) |
| miR-574-3p miR-30a-5p miR-922 |
CUL2 | Enhance chemosensitivity | Inhibit | (115) |
| miR-183-5p | MECP2 | Proliferation | Inhibit | (115) |
| miR-162 | TEAD3 | Enhance chemosensitivity | Inhibit | (115) |
| miR-146a | PI3K/AKT | Enhance chemosensitivity | Inhibit | (116) |
| miR-451 | ABCB1 | Enhance chemosensitivity | Promote | (117) |
| miR-186 | ABCB1 | Enhance chemosensitivity | Promote | (118) |
| miR-770-5p | ERCC2 | Enhance chemosensitivity | Promote | (119) |
| miR-376c | ALK7 | Enhance chemosensitivity | Promote | (120) |
| miR-130a miR-374a |
MDR1/PTEN | Enhance chemosensitivity | Promote | (121) |
| miR-489 | AKT3 | Enhance chemosensitivity | Promote | (122) |
| miR-134 | NF-κB1/c-Rel/ELK1 | Enhance chemosensitivity | Inhibit | (123) |