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. 2022 Nov 10;13:1009056. doi: 10.3389/fgene.2022.1009056

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Copyright © 2022 Wang, Jiang, Qi, Xu, Yang and Mi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Tumor microenvironment score and immune cell infiltration. (A): StromalScore, ImmuneScore and ESTIMATEScore of PAIP2 low expression group were significantly higher than those of PAIP2 high expression group (*represented p < 0.05, ** represented p < 0.01 and *** represented p < 0.001). (B): The expression of PAIP2 was significantly positively correlated with the infiltration of Macrophages M2, Mast cells resting, T cells CD4 memory resting and Neutrophils. It was significantly negatively correlated with T cells follicular helper, T cells CD8, T cells regulatory, plasma cells, NK cells activated, T cells CD4 memory activated and B cells memory.