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. 2022 Nov 23;10(11):e004712. doi: 10.1136/jitc-2022-004712

Figure 4.

Figure 4

CD47 expression regulates cytotoxic T cell bioenergetics. Cell respiratory measurements were acquired to determine the impact of CD47 on glycolysis of (A–C) WT and CD47- Jurkat T cells, (D, E) naïve and activated WT and cd47-/- CD8+ T cells and (F) WT and CD47 targeted (CD47(-)) Pmel-1 CD8+ T cells exposed to TSP1 (*p<0.05, n=3). ECAR, extracellular acidification rate; TSP1, thrombospondin-1; WT, wild type.