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. 2022 Nov 10;12:1057560. doi: 10.3389/fonc.2022.1057560

Table 3.

Treatment-related adverse events in the two groups.

TACE+AC (n = 34) TACE+A (n = 68) P value
Adverse events
Toxicity grade 1/2 3/4 1/2 3/4
TACE-related
Diarrhea 6 17.6% 1 2.9% 14 20.6% 5 7.4% 0.268
Transaminitis 13 38.2% 3 8.8% 26 38.2% 5 7.4% 1
Rash 4 63.7% 0 0.0% 11 16.1% 3 4.4% 0.409
Nausea with/without vomiting 22 64.7% 2 5.9% 31 45.6% 5 7.4% 0.135
Abdominal pain 19 55.9% 4 11.7% 42 61.7% 9 13.2% 0.641
Fatigue 7 29.0% 0 0.0% 4 5.8% 3 4.4% 0.221
Fever 19 26.5% 3 8.8% 33 48.5% 0 0.0% 0.144
Leukopenia 6 17.6% 1 2.9% 8 11.7% 0 0.249
Neutropenia 5 14.7% 1 2.9% 6 8.8% 0 0.208
Lymphopenia 4 11.8% 1 2.9% 5 7.4% 1 1.5% 0.499
Thrombopenia 7 20.6% 0 0.0% 12 17.6% 0 0.0% 0.789
Anemia 6 17.6% 0 0.0% 8 11.7% 0 0.0% 0.543
Decreased appetite 6 17.6% 0 0.0% 24 35.2% 0 0.0% 0.071
Apatinib and Camrelizumab -related Hand-foot skin reactions 7 11.7% 3 8.8% 20 29.4% 8 11.7% 0.283
Hypertension 11 32.4% 4 11.7% 16 23.5% 11 16.1% 0.676
REECP 7 29.0% 1 2.9% 0 0
all 34 100.0% 11 32.3% 64 100.0% 16 23.5% 0.298