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. 2022 Nov 10;13:1052720. doi: 10.3389/fgene.2022.1052720

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Copyright © 2022 Wang, Huang, Liu, Li, Wang, Li, Li and Han.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Construction and validation of an ICD risk model. (A,B) Lasso-Cox analysis identifies seven ICD genes associated with overall survival in BC. (C) Prognostic heatmap showing the relationship between different risk scores of the ICD risk model, patient survival events, and changes in gene expression. (D,E) Survival analysis plot showing the risk model has valid prognostic significance in both the TCGA (p = 2.3 × 10⁻⁷) and GSE58812 (p = 2.5 × 10⁻⁸) cohorts.