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. 2022 Nov 10;13:1038272. doi: 10.3389/fphar.2022.1038272

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Copyright © 2022 Chen, Zhang, Wang, Li, Yuan, Li, Zuo, Feng, Li, Chen and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Functional enrichment analysis of the transcriptome of the consensus clusters. (A) Top 20 differentially expressed KEGG gene sets. (B) Top 20 differentially expressed HALLMARKS gene sets. (C) The top five pathways with the highest normalized enrichment score in the KEGG gene sets between two clusters. (D) The top five pathways with the highest normalized enrichment score in the HALLMARKS gene sets between two clusters. (E) Pathways with high odds ratio and confidence in the KEGG gene sets. (F) Pathways with high odds ratio and confidence in the HALLMARKS gene sets.