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. 2022 Nov 10;13:1038272. doi: 10.3389/fphar.2022.1038272

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Copyright © 2022 Chen, Zhang, Wang, Li, Yuan, Li, Zuo, Feng, Li, Chen and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differences in expression of immunotherapy targets and response to ICIs between two PuMRS risk groups. (A) The expression level of 33 immunotherapy-related genes in two risk groups. (B) Analyses of correlations of PuMRS with the expression of CD274, CD276, CD44, and PDCD1. (C) TIP scores and related gene expression levels between two risk groups in TCGA datasets. (D) Analyses of correlations of PuMRS with the TIP score. (E) Percentage of predicted CTL level in each risk group. (F) Percentage of predicted responders to immune checkpoint inhibitors therapy in each risk group.