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. Author manuscript; available in PMC: 2023 Jul 22.
Published in final edited form as: Circ Res. 2022 Jun 14;131(3):222–235. doi: 10.1161/CIRCRESAHA.121.319817

Figure 3: Exacerbated Pressure Overload HF in 3-MST KO Mice.

Figure 3:

(A) LV end-diastolic diameter (LVEDD) and (B) LV ejection fraction (LVEF) throughout the 12 weeks study for 3-MST KO and wildtype (WT) control mice. (C) LV end-diastolic pressure (LVEDP), (D) LV relaxation constant Tau, (E) circulating B-type natriuretic peptide (BNP), (F) aortic vascular reactivity to acetylcholine (Ach), (G) aortic vascular reactivity to sodium nitroprusside (SNP), and (H) treadmill running duration in 3-MST KO and control mice at 12 weeks post TAC. Circles inside bars indicates samples size. Data in (A), (B), (F) and (G) were analyzed with ordinary 2-way ANOVA; data in other panels were analyzed with student unpaired 2-tailed t test. Data are presented as mean ± SD.