Table 1.
Biochemical profile of the hyperthyroid patients’ pre- and post-treatment using carbimazole as antithyroid medication.
| Parameters | Hyperthyroid | Euthyroid | p-value |
|---|---|---|---|
| Patients number | 20 | ||
| Age (years) | 40 ± 11.5 | ||
| Glucose (mmol/L) | 5.5 ± 0.7 | 5.6 ± 0.6 | 0.63 |
| Urea (mmol/L) | 4.6 ± 0.5 | 4.8 ± 0.5 | 0.21 |
| Creatinine (umol/L) | 62.1 ± 10.7 | 65.8 ± 11.0 | 0.45 |
| Sodium (mmol/L) | 139.2 ± 1.9 | 139.1 ± 0.4 | 0.81 |
| Potassium (mmol/L) | 4.4 ± 0.1 | 4.4 ± 0.2 | 1.00 |
| Aspartate transaminase (IU/L) | 33.9 ± 8.9 | 30.6 ± 4.2 | 0.30 |
| Alanine transaminase (IU/L) | 17.1 ± 4.8 | 15.2 ± 1.9 | 0.25 |
| Alkaline phosphatase (IU/L) | 113.9 ± 52.9 | 119.8 ± 28.4 | 0.76 |
| FT4 (pmol/L) | 34.9 ± 9.8 | 16.9 ± 2.9 | < 0.0001* |
| TSH (mIU/L) | 0.014 ± 0.02 | 0.7 ± 0.5 | < 0.0001* |
| Total cholesterol (mmol/L) | 4.5 ± 1.2 | 4.8 ± 1.0 | 0.55 |
| LDL cholesterol (mmol/L) | 2.6 ± 0.8 | 3.0 ± 0.8 | 0.27 |
| TG (mmol/L) | 1.0 ± 0.7 | 0.8 ± 0.5 | 0.31 |
| HDL cholesterol (mmol/L) | 1 ± 0.3 | 1.3 ± 0.3 | 0.03* |
*Indicate statistically significant alterations (p-value < 0.05).
FT4, free thyroxine; TSH, thyroid-stimulating hormone; LDL, low-density lipoprotein; TG, triglycerides; HDL, high-density lipoprotein.