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. 2022 Nov 10;13:921511. doi: 10.3389/fphar.2022.921511

FIGURE 2.

FIGURE 2

Effect of Buddleja globosa Hope (BG) extracts on Pseudomonas aeruginosa biofilm formation. P. aeruginosa was treated for 24 h with a hydroalcoholic BG extract (BG-126) (A), spray-dried BG extract (BG-SD) (B), spray-dried BG extract with Soluplus® (BG-SD SP) (C), and spray-dried BG extract with PVP (BG-SD PVP) (D) were stained with crystal violet (CV) for the determination of the biomass of biofilms based on the amount of CV retained by the stained wells. The results are expressed as changes in %biomass with respect to the control group. Asterisks on bars indicate a statistically significant difference with respect to the untreated control, and asterisks on brackets indicate differences between the BG formulations and the excipients. *p ˂ 0.05, **p ˂ 0.01, ***p ˂ 0.01, and ****p ˂ 0.01.