. 2022 Oct 24;60(12):530–538. doi: 10.5414/CP204257

Table 2. Pharmacokinetic parameters after single oral dose of curcumin preparations.

Preparation	TS-P1 capsule						CR-043P capsule						CR-033P capsule
	AUC_0–24h	AUC_0–12h	AUC_0–24h dose adjusted	C_max	t_max	T_1/2 (complete case)	AUC_0–24h	AUC_0–12h	AUC_0–24h dose adjusted	C_max	t_max	T_1/2 (complete case)	AUC_0–24h	AUC_0–12h	AUC_0–24h dose adjusted	C_max	t_max	T_1/2 (complete case)
	(ng/mL×h)	(ng/mL×h)	(ng/mL×h)	(ng/mL)	(h)	(h)	(ng/mL×h)	(ng/mL×h)	(ng/mL×h)	(ng/mL)	(h)	(h)	(ng/mL×h)	(ng/mL×h)	(ng/mL×h)	(ng/mL)	(h)	(h)
Mean	1,168.88	889.76	25.98	179.91	2.18	6.23	1,247.32	739.46	13.86	104.90	6.59	10.18	1,345.39	837.56	14.95	108.60	6.50	8.89
SD	635.95	491.80	14.13	109.67	1.33	2.70	615.40	406.49	6.84	85.79	5.22	3.86	580.35	397.43	6.45	54.68	2.65	4.07
Geometric mean	1,036.81	791.16	23.04	152.63	1.82	5.72	1,092.63	648.13	12.14	85.95	4.88	10.03	1,235.61	762.92	13.73	97.59	5.76	8.60
Median	953.62	724.56	21.19	162.78	2.00	5.85	1,179.90	675.37	13.11	96.24	4.00	10.46	1,307.31	795.71	14.53	100.83	8.00	8.16
Min.	511.97	414.89	11.38	55.73	1.0	2.38	204.41	156.35	2.27	18.03	1.0	5.42	503.12	397.94	5.59	43.69	1.0	4.12
Max.	2,756.17	2,202.85	61.25	500.37	4.0	14.37	2,894.74	2,111.02	32.16	454.30	24.0	18.25	3,031.31	2,116.61	33.68	281.91	12.0	15.97