Table 3.
Clusters exhibiting the influence of male and female sex on ALFF in the MDD and HC groups.
| Brain area | Cluster size | Peak MNI coordinates | Peak F value | ||
|---|---|---|---|---|---|
| X | Y | Z | |||
| Main effect of diagnosis groups | |||||
| A The left Olfactory The left orbital inferior frontal gyrus |
44 | −24 | 9 | −24 | 20.81 |
| B The left caudate | 73 | −15 | 3 | 18 | 22.61 |
| C The right calcarine The left calcarine |
98 | 6 | −75 | 15 | 14.03 |
| D The left thalamus | 31 | −12 | −18 | 15 | 21.65 |
| E The left precentral gyrus The left postcentral gyrus |
60 | −51 | −3 | 36 | 28.39 |
| Main effect of gender groups | |||||
| A The left putamen | 77 | −21 | 6 | −3 | 17.32 |
| B The left lingual gyrus The left calcarine The left inferior temporal gyrus |
114 | −36 | −42 | −15 | 22.17 |
| C The right orbital inferior frontal gyrus | 57 | 39 | 30 | −21 | 39.5 |
| D The right orbital middle frontal gyrus | 48 | 42 | 57 | −12 | 24.27 |
| E The right orbital medial frontal gyrus | 36 | 6 | 69 | −3 | 15.16 |
| F The right calcarine | 28 | 12 | −60 | 12 | 16.44 |
| G The left middle occipital lobe | 184 | −36 | −93 | 3 | 29.42 |
| H The bilateral thalamus | 40 | 0 | −12 | 9 | 23.65 |
| I The right middle occipital lobe | 139 | 39 | −84 | 21 | 22.32 |
| J The left superior temporal gyrus | 69 | −45 | −39 | 21 | 24.82 |
| K The right median cingulate gyrus | 31 | 9 | −24 | 42 | 14.45 |
| Diagnosis group×Gender groups interaction | |||||
| The right superior occipital gyrus | 24 | 21 | −90 | 6 | 15.88 |
These findings correspond to a corrected P < 0.05 by GRF correction.