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. 2022 Nov 10;9:1038114. doi: 10.3389/fcvm.2022.1038114

FIGURE 4.

FIGURE 4

IL-1β induces Activin A gene expression in cardiac fibroblasts. (A) The effect of inflammatory cytokines, IL-1β, IL-6, and oncostatin M on gene expression in cardiac fibroblasts. (B) The concentration of Activin A in control- and IL-1β-treated cells. (C) The effect of IL-1β on induced pluripotent stem cell-derived CM contractility (vertical lines indicate media changes). One-way ANOVA was used to determine significance. ****P < 0.0001. ActA, Activin A; CM, cardiomyocyte.