Figure 10.

Schematic of (A) bull P1 and (B) human P1 protamine sequences showing candidate residue pairs for disulfide/crosslink formation. Only the top three pairs from Table 3 for bull and human P1 are shown here. Red lines connect residue pairs that were both predicted by the MD simulation and also have been suggested by at least one previous model, while blue lines connect residue pairs predicted by only the MD simulation. The dotted green line connects a residue pair proposed by a previous model that is not predicted by our MD simulation.