TABLE 3.
Comparison of clinical outcomes of different morphological groups.
Morphological parameter | Positive hCG (%) | P1 | OR | 95% CI | P2 | Clinical pregnancy rate (%) | P1 | OR | 95% CI | P2 | Live birth (%) | P1 | OR | 95% CI | P2 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Blastocyst | |||||||||||||||
Good | 59.0% (23/39) | 0.034 | 2.309 | 1.067–4.996 | 0.72 | 56.4% (22/39) | 0.025 | 2.416 | 1.115–5.232 | 0.54 | 48.7% (19/39) | 0.017 | 2.602 | 1.182–5.727 | 0.44 |
Medium | 54.6% (77/141) | 0.018 | 1.932 | 1.119–3.338 | ref | 49.6% (70/141) | 0.031 | 1.840 | 1.059–3.199 | ref | 40.4% (57/141) | 0.038 | 1.859 | 1.036–3.333 | Ref |
Poor | 38.4% (33/86) | Ref | 34.9% (30/86) | Ref | 26.7% (23/86) | Ref | |||||||||
ICM grade | |||||||||||||||
A | 58.8% (20/34) | 0.054 | 2.619 | 0.983–6.981 | 0.49 | 55.9% (19/34) | 0.053 | 2.648 | 0.987–7.108 | 0.39 | 47.1% (16/34) | 0.024 | 3.429 | 1.176–9.994 | 0.44 |
B | 51.0% (101/198) | 0.094 | 1.909 | 0.896–4.068 | Ref | 46.5% (92/198) | 0.130 | 1.815 | 0.840–3.923 | Ref | 38.4% (76/198) | 0.051 | 2.403 | 0.997–5.789 | Ref |
C | 35.3% (12/34) | Ref | 32.4% (11/34) | Ref | 20.6% (7/34) | Ref | |||||||||
TE grade | |||||||||||||||
A | 52.9% (9/17) | 0.307 | 1.761 | 0.594–5.220 | 0.81 | 52.9% (9/17) | 0.202 | 2.036 | 0.684–6.063 | 0.90 | 41.2% (7/17) | 0.337 | 1.729 | 0.565–5.291 | 0.88 |
B | 53.2% (101/190) | 0.059 | 1.776 | 0.979–3.223 | Ref | 48.4% (92/190) | 0.086 | 1.699 | 0.928–3.108 | Ref | 39.5% (75/190) | 0.140 | 1.611 | 0.855–3.038 | Ref |
C | 39.0% (23/59) | Ref | 35.6% (21/59) | Ref | 28.8% (17/59) | Ref | |||||||||
Expansion degree | |||||||||||||||
6 | 25% (4/16) | 0.047 | 0.308 | 0.097–0.984 | 0.11 | 25% (4/16) | 0.090 | 0.367 | 0.115–1.170 | 0.18 | 25% (4/16) | 0.260 | 0.513 | 0.16–1.639 | 0.94 |
5 | 47.4% (9/19) | 0.701 | 0.832 | 0.326–2.124 | Ref | 42.1% (8/19) | 0.644 | 0.800 | 0.31–2.062 | Ref | 21.1% (4/19) | 0.124 | 0.410 | 0.132–1.275 | Ref |
4 + 3 | 51.9% (120/231) | Ref | — | — | — | 47.6% (110/231) | Ref | — | — | — | 39.4% (91/231) | Ref | — | — | — |
Note: OR, odds ratio; CI, confidence interval; TE, trophectoderm; ICM, inner cell mass; vs., versus; Ref, reference.