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. 2022 Nov 10;13:964360. doi: 10.3389/fphys.2022.964360

TABLE 3.

Comparison of clinical outcomes of different morphological groups.

Morphological parameter Positive hCG (%) P1 OR 95% CI P2 Clinical pregnancy rate (%) P1 OR 95% CI P2 Live birth (%) P1 OR 95% CI P2
Blastocyst
 Good 59.0% (23/39) 0.034 2.309 1.067–4.996 0.72 56.4% (22/39) 0.025 2.416 1.115–5.232 0.54 48.7% (19/39) 0.017 2.602 1.182–5.727 0.44
 Medium 54.6% (77/141) 0.018 1.932 1.119–3.338 ref 49.6% (70/141) 0.031 1.840 1.059–3.199 ref 40.4% (57/141) 0.038 1.859 1.036–3.333 Ref
 Poor 38.4% (33/86) Ref 34.9% (30/86) Ref 26.7% (23/86) Ref
ICM grade
 A 58.8% (20/34) 0.054 2.619 0.983–6.981 0.49 55.9% (19/34) 0.053 2.648 0.987–7.108 0.39 47.1% (16/34) 0.024 3.429 1.176–9.994 0.44
 B 51.0% (101/198) 0.094 1.909 0.896–4.068 Ref 46.5% (92/198) 0.130 1.815 0.840–3.923 Ref 38.4% (76/198) 0.051 2.403 0.997–5.789 Ref
 C 35.3% (12/34) Ref 32.4% (11/34) Ref 20.6% (7/34) Ref
TE grade
 A 52.9% (9/17) 0.307 1.761 0.594–5.220 0.81 52.9% (9/17) 0.202 2.036 0.684–6.063 0.90 41.2% (7/17) 0.337 1.729 0.565–5.291 0.88
 B 53.2% (101/190) 0.059 1.776 0.979–3.223 Ref 48.4% (92/190) 0.086 1.699 0.928–3.108 Ref 39.5% (75/190) 0.140 1.611 0.855–3.038 Ref
 C 39.0% (23/59) Ref 35.6% (21/59) Ref 28.8% (17/59) Ref
Expansion degree
 6 25% (4/16) 0.047 0.308 0.097–0.984 0.11 25% (4/16) 0.090 0.367 0.115–1.170 0.18 25% (4/16) 0.260 0.513 0.16–1.639 0.94
 5 47.4% (9/19) 0.701 0.832 0.326–2.124 Ref 42.1% (8/19) 0.644 0.800 0.31–2.062 Ref 21.1% (4/19) 0.124 0.410 0.132–1.275 Ref
 4 + 3 51.9% (120/231) Ref 47.6% (110/231) Ref 39.4% (91/231) Ref

Note: OR, odds ratio; CI, confidence interval; TE, trophectoderm; ICM, inner cell mass; vs., versus; Ref, reference.