TABLE 3.

Multivariable Cox regression analysis for cardiovascular disease events and all-cause mortality.

		Model 1		Model 2		Model 3
		P	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)
CVD	1		Reference		Reference		Reference
	2	>0.05	1.04 (0.42∼2.62)	>0.05	0.90 (0.36∼2.27)	>0.05	0.78 (0.31∼1.98)
	3	<0.01	2.00 (1.36∼2.93)	<0.01	1.84 (1.25∼2.70)	<0.01*	1.43 (0.97∼2.10)
	4	<0.01	4.17 (2.48∼7.00)	<0.01	3.17 (1.87∼5.39)	<0.01*	2.38 (1.40∼4.05)
All-cause mortality	1		Reference		Reference		Reference
	2	>0.05	1.63 (0.70∼3.81)	>0.05	1.66 (0.71∼3.89)	>0.05	1.59 (0.68∼3.74)
	3	<0.01	1.86 (1.31∼2.66)	<0.01	1.86 (1.30∼2.66)	<0.01*	1.73 (1.20∼2.48)
	4	<0.01	2.32 (1.36∼3.94)	<0.01	2.25 (1.30∼3.88)	<0.01*	2.08 (1.20∼3.59)
CI	1		Reference		Reference		Reference
	2	>0.05	0.99 (0.30∼3.22)	>0.05	0.87 (0.27∼2.88)	>0.05	0.78 (0.31∼1.98)
	3	<0.01	2.19 (1.37∼3.49)	<0.01	1.99 (1.25∼3.16)	>0.05	1.50 (0.94∼2.39)
	4	<0.01	4.50 (2.42∼8.37)	<0.01	3.35 (1.78∼6.31)	<0.01*	2.47 (1.31∼4.67)
MI	1		Reference		Reference		Reference
	2	>0.05	0.71 (0.09∼5.44)	>0.05	0.60 (0.08∼4.62)	>0.05	0.50 (0.07∼3.91)
	3	<0.01	1.76 (0.83∼3.75)	>0.05	1.55 (0.73∼3.32)	>0.05	1.36 (0.63∼2.94)
	4	<0.01	1.99 (0.56∼7.11)	>0.05	1.56 (0.43∼5.65)	>0.05	1.25 (0.34∼4.58)

Model 1 corrected for age and gender. Model 2 further corrected BMI, total cholesterol (TC), and high-density lipoprotein (HDL) based on Model 1. Model 3 further corrected smoking, drinking alcohol, hypertension, diabetes, and taking hypotensive drugs based on Model 2. HR, hazard ratios; 95% CI, 95% confidence interval; CVD, cardiovascular disease; CI, cerebral ischemia; MI, myocardial infarction. *Statistically significant (P < 0.05).