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. 2022 Nov 10;12:1000146. doi: 10.3389/fonc.2022.1000146

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Copyright © 2022 Li, Meng, Xue, Teng, Chen, Zhang, Xu, Wang, Yu, Ou, Wu and Jia

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The comparisons of somatic mutation characteristics and mutation types among colorectal cancer patients with different tumor anatomic locations and genetic interaction analysis of different tumor anatomic locations. (A, B) The bar plots comparing somatic mutation and pathway alteration rates among patients with different tumor anatomic locations (right-sided colon, N=31; left-sided colon, N=36; rectal, N=66). (C) The box plots comparing differences in mutation types among patients with different tumor anatomic locations (right-sided colon, N=31; left-sided colon, N=36; rectal, N=66). (D-F) Genetic interaction analysis of different tumor anatomic locations. *p < 0.05, **p < 0.01, ***p < 0.001.