Table 3.
G6PD activity and reticulocyte count in the G6PD deficiency, intermediate, and normal newborn groups
| Parameter | G6PD Normal | G6PD Intermediate | G6PD Deficiency | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Total | Male | Female | Total | Male | Female | Total | Male | Female | |
| Spectrophotometric assay (n) | 837 | 423 | 414 | 116 | 29 | 87 | 62 | 50 | 12 |
| G6PD activity (U/g Hb) | 10.48 ± 2.18 | 10.52 ± 2.15 | 10.45 ± 2.23 | 6.34 ± 2.40 | 7.63 ± 1.01 | 6.04 ± 1.92 | 1.33 ± 0.75 | 1.21 ± 0.76 | 1.56 ± 1.67 |
| Reticulocyte count (%) | 4.78 ± 1.29 | 4.56 ± 1.20 | 5.01 ± 1.33 | 5.03 ± 1.43 | 4.31 ± 1.69 | 5.27 ± 1.25 | 5.82 ± 1.73a | 5.86 ± 1.90b | 5.65 ± 0.69c |
| Automated UV enzymatic assay (n) | 791 | 403 | 388 | 158 | 47 | 111 | 66 | 52 | 14 |
| G6PD activity (U/g Hb) | 27.45 ± 6.63 | 27.26 ± 6.68 | 27.50 ± 6.63 | 16.49 ± 6.37 | 18.26 ± 2.81 | 14.75 ± 6.22 | 1.81 ± 0.90 | 1.76 ± 0.70 | 2.11 ± 5.44 |
| Reticulocyte count (%) | 4.82 ± 1.29 | 4.60 ± 1.20 | 5.04 ± 1.34 | 4.76 ± 1.37 | 3.94 ± 1.25b | 5.10 ± 1.28 | 5.83 ± 1.71a | 5.91 ± 1.88b | 5.52 ± 0.75c |
Values are expressed as the mean ± SD
a compared to the normal group (p < 0.001) (t-test)
b compared to males in the normal group (p < 0.001) (t-test)
c compared to females in the normal group (p < 0.05) (t-test)