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. 2022 Nov 23;21:242. doi: 10.1186/s12934-022-01961-8

Table 3.

Organic acid distribution for bioreactor cultivations based on the sampling points summarized in Table 2

Fermentation No. Organic acid distribution [%]a
Malate Succinate Fumarate Pyruvate α-Ketoglutarate Oxalate Citrate
I 47.0 ± 1.7 39.7 ± 2.4 5.3 ± 0.3 3.4 ± 0.7 0.3 ± 0.0 3.3 ± 0.1 1.1 ± 0.2
II 47.4 ± 0.6 40.7 ± 0.1 5.4 ± 0.1 2.3 ± 0.5 0.3 ± 0.0 3.0 ± 0.1 0.9 ± 0.0
III 51.7 ± 0.8 42.1 ± 0.5 3.8 ± 0.1 1.2 ± 0.2 0.2 ± 0.0 0.1 ± 0.0 1.0 ± 0.0
IV 51.0 ± 0.3 42.5 ± 0.4 4.2 ± 0.4 1.3 ± 0.0 0.1 ± 0.0 0.6 ± 0.2 0.3 ± 0.2
V 51.6 ± 0.6 42.0 ± 0.5 4.3 ± 0.0 1.5 ± 0.1 0.0 ± 0.0 0.6 ± 0.1 0.0 ± 0.0
VI 54.5 ± 0.1 40.2 ± 0.2 3.3 ± 0.2 0.6 ± 0.1 0.2 ± 0.0 0.9 ± 0.2 0.5 ± 0.1
VII 50.2 ± 2.7 43.1 ± 2.8 2.9 ± 0.2 1.6 ± 0.1 0.2 ± 0.0 0.8 ± 0.6 1.1 ± 0.1

aValues were calculated as the percentage of the total acid concentration as given in Table 2