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. 2022 Nov 24;20:163. doi: 10.1186/s12958-022-01030-0

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 9 — Differential stroma expression profiles among mice with apoptotic luminal epithelia. A Principal component analysis of gene expression data from high-fat diet endometrial stroma based on luminal epithelia CC3, > 10% or < 10%. B Volcano plot of expressed genes in stroma of two groups. Significant differentially expressed genes (FDR < 0.05) among > 10% CC3 epithelia compared to < 10% CC3 epithelia are highlighted in red. Genes with FDR < 0.001 are denoted with gene symbols. C,D Enrichment analysis for GO biological processes for upregulated genes (n = 1,702) (C) or downregulated genes (n = 1,660) (D)