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. 2022 Nov 23;12:20167. doi: 10.1038/s41598-022-24611-w

Table 1.

Top 25 cis-eQTLs (p < 5e−8).

Gene Symbol SNP Chr SNP position Gene start position R2 Beta log10P OA EA EAF Type
PPIE rs7513045 1 39,738,494 39,692,182 0.84 11.40 − 1029.25 G T 0.36 protein_coding
CCDC163 rs4660860 1 45,480,561 45,493,866 0.90 − 3.10 − 1286.89 T A 0.30 protein_coding
CYP26B1 rs13430651 2 72,215,195 72,129,238 0.81 1.98 − 920.005 G A 0.15 protein_coding
MAP3K2-DT rs2276683 2 127,389,186 127,389,130 0.88 − 1.61 − 1176.37 G C 0.23 lincRNA
SLC12A7 rs35188965 5 1,104,823 1,050,384 0.81 − 29.87 − 915.459 C T 0.44 protein_coding
ENC1 rs112772452 5 74,631,048 74,627,406 0.83 14.53 − 986.798 CA C 0.11 protein_coding
ERAP2 rs2910686 5 96,916,885 96,875,939 0.85 36.98 − 1044.91 T C 0.43 protein_coding
BTNL3 rs72494581 5 181,003,797 180,988,845 0.82 13.52 − 950.405 T C 0.30 protein_coding
HLA-DRB5 rs68176300 6 32,558,713 32,517,353 0.83 − 178.13 − 1003.76 T G 0.15 protein_coding
AL512625.3 rs1845054 9 62,906,092 62,856,999 0.83 − 1.19 − 993.655 T C 0.13 lincRNA
CUTALP rs13299616 9 120,832,525 120,824,828 0.86 − 23.25 − 1092.88 T C 0.40 transcribed_unitary_pseudogene
LDHC rs201993031 11 18,412,985 18,412,318 0.82 0.16 − 946.833 CCCTTCCTT C 0.12 protein_coding
ACCS rs2074038 11 44,066,439 44,065,925 0.83 16.69 − 997.26 G T 0.11 protein_coding
FADS2 rs968567 11 61,828,092 61,792,980 0.88 31.41 − 1186.37 C T 0.17 protein_coding
XRRA1 rs10899051 11 74,931,506 74,807,739 0.91 5.38 − 1327.88 G A 0.26 protein_coding
B4GALNT3 rs1056008 12 553,672 460,364 0.85 6.71 − 1043.34 T C 0.25 protein_coding
DDX11 rs3891006 12 31,073,506 31,073,860 0.86 − 13.25 − 1102.08 A G 0.44 protein_coding
RPS26 rs1131017 12 56,042,145 56,041,351 0.81 − 134.34 − 929.902 C G 0.39 protein_coding
C17orf97 rs7503725 17 410,351 410,325 0.85 1.89 − 1055.68 G T 0.25 protein_coding
AC126544.2 rs2696531 17 46,278,268 45,586,452 0.86 1.04 − 1097.79 C A 0.21 lincRNA
SPATA20 rs9890200 17 50,547,162 50,543,058 0.81 − 1.01 − 34.173 A C 0.37 protein_coding
CEACAMP3 rs3745936 19 41,586,462 41,599,735 0.84 1.11 − 040.05 A T 0.22 transcribed_unprocessed_pseudogene
PWP2 rs2277806 21 44,089,769 44,107,373 0.87 3.16 − 139.85 A C 0.19 protein_coding
GATD3A rs3788104 21 44,092,213 44,133,610 0.86 4.25 − 104.35 G A 0.18 protein_coding
FAM118A rs576259663 22 45,363,712 45,308,968 0.86 43.45 − 1108.47 T TA 0.12 protein_coding

EA effect allele, OA the other allele, EAF effect allele frequency; R2 variance explained by the lead eQTL (SNP).