Table 1.
Gene Symbol | SNP | Chr | SNP position | Gene start position | R2 | Beta | log10P | OA | EA | EAF | Type |
---|---|---|---|---|---|---|---|---|---|---|---|
PPIE | rs7513045 | 1 | 39,738,494 | 39,692,182 | 0.84 | 11.40 | − 1029.25 | G | T | 0.36 | protein_coding |
CCDC163 | rs4660860 | 1 | 45,480,561 | 45,493,866 | 0.90 | − 3.10 | − 1286.89 | T | A | 0.30 | protein_coding |
CYP26B1 | rs13430651 | 2 | 72,215,195 | 72,129,238 | 0.81 | 1.98 | − 920.005 | G | A | 0.15 | protein_coding |
MAP3K2-DT | rs2276683 | 2 | 127,389,186 | 127,389,130 | 0.88 | − 1.61 | − 1176.37 | G | C | 0.23 | lincRNA |
SLC12A7 | rs35188965 | 5 | 1,104,823 | 1,050,384 | 0.81 | − 29.87 | − 915.459 | C | T | 0.44 | protein_coding |
ENC1 | rs112772452 | 5 | 74,631,048 | 74,627,406 | 0.83 | 14.53 | − 986.798 | CA | C | 0.11 | protein_coding |
ERAP2 | rs2910686 | 5 | 96,916,885 | 96,875,939 | 0.85 | 36.98 | − 1044.91 | T | C | 0.43 | protein_coding |
BTNL3 | rs72494581 | 5 | 181,003,797 | 180,988,845 | 0.82 | 13.52 | − 950.405 | T | C | 0.30 | protein_coding |
HLA-DRB5 | rs68176300 | 6 | 32,558,713 | 32,517,353 | 0.83 | − 178.13 | − 1003.76 | T | G | 0.15 | protein_coding |
AL512625.3 | rs1845054 | 9 | 62,906,092 | 62,856,999 | 0.83 | − 1.19 | − 993.655 | T | C | 0.13 | lincRNA |
CUTALP | rs13299616 | 9 | 120,832,525 | 120,824,828 | 0.86 | − 23.25 | − 1092.88 | T | C | 0.40 | transcribed_unitary_pseudogene |
LDHC | rs201993031 | 11 | 18,412,985 | 18,412,318 | 0.82 | 0.16 | − 946.833 | CCCTTCCTT | C | 0.12 | protein_coding |
ACCS | rs2074038 | 11 | 44,066,439 | 44,065,925 | 0.83 | 16.69 | − 997.26 | G | T | 0.11 | protein_coding |
FADS2 | rs968567 | 11 | 61,828,092 | 61,792,980 | 0.88 | 31.41 | − 1186.37 | C | T | 0.17 | protein_coding |
XRRA1 | rs10899051 | 11 | 74,931,506 | 74,807,739 | 0.91 | 5.38 | − 1327.88 | G | A | 0.26 | protein_coding |
B4GALNT3 | rs1056008 | 12 | 553,672 | 460,364 | 0.85 | 6.71 | − 1043.34 | T | C | 0.25 | protein_coding |
DDX11 | rs3891006 | 12 | 31,073,506 | 31,073,860 | 0.86 | − 13.25 | − 1102.08 | A | G | 0.44 | protein_coding |
RPS26 | rs1131017 | 12 | 56,042,145 | 56,041,351 | 0.81 | − 134.34 | − 929.902 | C | G | 0.39 | protein_coding |
C17orf97 | rs7503725 | 17 | 410,351 | 410,325 | 0.85 | 1.89 | − 1055.68 | G | T | 0.25 | protein_coding |
AC126544.2 | rs2696531 | 17 | 46,278,268 | 45,586,452 | 0.86 | 1.04 | − 1097.79 | C | A | 0.21 | lincRNA |
SPATA20 | rs9890200 | 17 | 50,547,162 | 50,543,058 | 0.81 | − 1.01 | − 34.173 | A | C | 0.37 | protein_coding |
CEACAMP3 | rs3745936 | 19 | 41,586,462 | 41,599,735 | 0.84 | 1.11 | − 040.05 | A | T | 0.22 | transcribed_unprocessed_pseudogene |
PWP2 | rs2277806 | 21 | 44,089,769 | 44,107,373 | 0.87 | 3.16 | − 139.85 | A | C | 0.19 | protein_coding |
GATD3A | rs3788104 | 21 | 44,092,213 | 44,133,610 | 0.86 | 4.25 | − 104.35 | G | A | 0.18 | protein_coding |
FAM118A | rs576259663 | 22 | 45,363,712 | 45,308,968 | 0.86 | 43.45 | − 1108.47 | T | TA | 0.12 | protein_coding |
EA effect allele, OA the other allele, EAF effect allele frequency; R2 variance explained by the lead eQTL (SNP).