Table 2.
Type 1 error rates of individual statistical methods.
| Sparsity | DESeq2 LRT | DESeq2 Wald | edgeR | Wilcoxon | ZIBSeq | ZIG Gaussian | ZIG Log Normal | ZINB | aSPU | oMiRKAT | aMiSPU | TMAT |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.3 | 0.000 | 0.000 | 0.000 | 0.017 | 0.002 | 0.000 | 0.000 | 0.000 | 0.014 | 0.014 | 0.014 | 0.014 |
| 0.5 | 0.037 | 0.037 | 0.026 | 0.006 | 0.031 | 0.094 | 0.000 | 0.043 | 0.042 | 0.042 | 0.042 | 0.042 |
| 0.7 | 0.000 | 0.000 | 0.000 | 0.013 | 0.000 | 0.009 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 |
| 0.8 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 |
Bold value indicates to inflated type I errors.