TABLE 2.
Significant main effect of group and sex and homeostatic model assessment (HOMA) interaction on functional connectivity density (FCD) and resting-state functional connectivity (rs-FC).
| Connectivity measure: Contrast | MNI coordinates | R 2 | F(31,112) | d/δ | CI 95% | BF10 |
| Cortical location of the peak vertex | ||||||
| lrFCD: Group × Sex | ||||||
| R precuneus (p = 0.03) | 7–47 55 | 0.13 | 21.9 | −1.37M | −1.8–−0.09 | 165E |
| srFCD: Group × HOMA-IR | ||||||
| L mOFC (p = 0.006) | −7 29–12 | 0.13 | 22.2 | −1.14M | −2.2–−0.04 | 124E |
| rs-FC L mOFC: Group | ||||||
| L PCC (p = 0.01) | −2–18 31 | 0.15 | 26 | 0.47S | 0.16–0.77 | 49.7VS |
| R Parahipocampal (p = 0.007) | 29–43–8 | 0.12 | 19.5 | −0.50S | −0.80–−0.20 | 12.5S |
| rs-FC L mOFC: Group × Sex | ||||||
| R IFG (pars opercularis) (p < 10–6) | 44 10 5 | 0.13 | 22.2 | −1.29M | −1.97–−0.61 | 353E |
| R STG (p = 0.008) | 64–24 2 | 0.15 | 25.8 | −0.99S | −1.55–−0.44 | 15.6S |
L, left; R, right; mOFC, medial orbitofrontal cortex; PCC, posterior cingulate cortex; IFG, inferior frontal gyrus; STG, superior temporal gyrus. BF10: magnitude of the evidence in favor of the alternative hypothesis (Eextreme, VSvery strong, Sstrong, Mmoderate).