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. 2022 Nov 10;13:979333. doi: 10.3389/fneur.2022.979333

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Copyright © 2022 Okadome, Yamaguchi, Mukaino, Sakata, Ogata, Shigeto, Isobe and Uehara.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The correlation between sleep-dependent learning effect and pathological spindles. In the six patients with interictal epileptic discharges (IEDs), a simple linear regression analysis was conducted between the change between Trials 1 and 2 of sleep-dependent learning effect and that of IED-coupled spindle density of each electrode. (A) The correlation coefficient is shown here. There was a significant negative linear correlation in C4 (β = −634, 95%CI = −858 to −410, P = 0.019), marked as white dots. (B) A scatter plot of the result for C4 is displayed.