Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Nov 10;12:993243. doi: 10.3389/fonc.2022.993243

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Xia, Wang, Qi, Long, Li, He, Pan, Guo and Hu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

miR-140 targets and represses OGT expression. (A, B) Overexpression of miR-140 represses the OGT mRNA levels in PC3 and DU145 cells. NC: Negative control. (C, D) Overexpression of miR-140 represses the OGT protein expression and O-GlcNAC levels in PC3 and DU145 cells. (E) The putative miR-140 binding sequence in the 3′UTR of OGT. Red, mutations of the miR-140 binding site in the OGT 3′UTR. (F) Analyses of the luciferase activity of the luciferase reporter plasmids containing either wild-type (WT) or mutant-type (MT) OGT 3′UTRs in HEK-293 cells. *p < 0.05; **p < 0.01; ***p < 0.001 (Student’s t-test).