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. 2022 Nov 10;13:944681. doi: 10.3389/fgene.2022.944681

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Copyright © 2022 Jin, Song, Wang, Zhu, Sun, Liu and Shi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Construction and validation of a PUS-based nomogram. (A) The coefficients of three optimal PUSs; (B) K-M analysis for OS of HCC patients stratified by PUSscore; (C–D) Association of PUSscore with tumor stage (C) and tumor grade (D); (E) Correlation of PUSscore with MKI67 expression; (F) Representative HE staining and immunohistochemical results of HCC tissues with different levels of PUSscore; (G) Multivariate Cox analysis of PUSscore and clinical factors; (H) Development of a nomogram based on PUSscore and tumor stage; (I) K-M analysis for OS of HCC patients stratified by nomogram points; (J) The time-dependent ROC curves of the nomogram; (K) The calibration curves for the nomogram.