TABLE 1.
Univariate Cox analysis of PUSs and clinical factors.
| Univariate analysis | ||||||
|---|---|---|---|---|---|---|
| Overall Survival (OS) | Progression Free Survival (PFS) | |||||
| Characteristics | TCGA-LIHC | LIRI-JP | TCGA-LIHC | |||
| HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | |
| DKC1 | 1.021(1.012-1.031) | <0.001 | 1.022(1.014-1.030) | <0.001 | 1.012(1.004-1.021) | 0.003 |
| PUS1 | 1.054(1.030-1.080) | <0.001 | 1.023(1.008-1.039) | 0.003 | 1.037(1.015-1.060) | 0.001 |
| PUS7 | 1.061(1.027-1.097) | <0.001 | 1.073(1.031-1.116) | <0.001 | 1.046(1.017-1.075) | 0.002 |
| PUSL1 | 1.026(1.012-1.041) | <0.001 | 1.026(1.007-1.046) | 0.008 | 1.005(0.989-1.022) | 0.529 |
| RPUSD1 | 1.019(1.005-1.034) | 0.007 | 1.037(1.005-1.069) | 0.024 | 1.003 (0.989-1.018) | 0.637 |
| RPUSD2 | 1.006(0.958-1.055) | 0.823 | 1.030(0.939-1.130) | 0.533 | 1.032(0.992-1.074) | 0.119 |
| RPUSD3 | 1.050(1.024-1.078) | <0.001 | 1.039(1.017-1.062) | <0.001 | 1.033(1.009-1.058) | 0.006 |
| Age | 1.010(0.996-1.025) | 0.174 | 1.003(0.973-1.034) | 0.863 | 0.994(0.982-1.005) | 0.280 |
| Gender (M/F) | 0.776(0.531-1.132) | 0.188 | 0.536(0.287-0.998) | 0.049 | 0.933(0.673-1.294) | 0.679 |
| Grade (G3-4/G1-2) | 1.141(0.784-1.661) | 0.490 | 1.151(0.841-1.574) | 0.380 | ||
| Stage (III-IV/I-II) | 2.500(1.721-3.632) | <0.001 | 2.479(1.355-4.533) | 0.003 | 2.213(1.596-3.068) | <0.001 |