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. 2022 Nov 10;13:1047781. doi: 10.3389/fimmu.2022.1047781

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Copyright © 2022 Ratnatunga, Tungatt, Proietti, Halstrom, Holt, Lutzky, Price, Doolan, Bell, Field, Kupz, Thomson and Miles

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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NanoString-based gene expression levels in CD4⁺ and CD8⁺ T cells in NTM-PD. (A) Statistical heatmap of upregulated (red) and downregulated (blue) genes in patients with active MAC, PostTx MAC, active MABS or persistent infection (MAC or MABS) compared to the control group (BronchC and HC). (B) Statistical heatmap of upregulated and downregulated genes in patients with active MABS infection compared to patients with active MAC infection. Independent t-tests were performed using GMine with correction for multiple comparisons (FDR). Significance (p-value) is shown by colour intensity.