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. 2022 Nov 10;13:1047781. doi: 10.3389/fimmu.2022.1047781

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Copyright © 2022 Ratnatunga, Tungatt, Proietti, Halstrom, Holt, Lutzky, Price, Doolan, Bell, Field, Kupz, Thomson and Miles

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relative expression of individual immune genes in CD4⁺ and CD8⁺ T cells. (A) Expression, as log2 counts, of immune genes that differentiate active infection [MAC (blue) and MABS (red)] from Controls [BronchC and HC (green)]. Levels of PostTx MAC (orange) and Persistent Infection (purple) and significance of comparisons are shown. (B) Expression of immune genes differentiating infecting species (MAC versu MABS) in active infection are shown as log2 counts of RNA copy numbers. Mean, and SD are shown in black bars. Comparisons between cohorts were performed by ANOVA with Tukeys post hoc test. P values were adjusted for multiple comparisons ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05.