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. 2022 Oct 31;11(11):2155. doi: 10.3390/antiox11112155

Figure 1.

Figure 1

Chronic ischemia initiates hibernation in cardiac myocytes. This adaptive response involves a coordinated change in gene expression leading to increased glucose uptake and glycolysis-dependent metabolism. On histology, hibernating myocardium is characterized by fewer and smaller mitochondria.