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Dysregulation of mitochondrial size and number can be observed in hibernating myocardium. Mesenchymal stem cells have shown to increase mitochondrial size and density when used alongside CABG (A,B). Comparing healthy and hibernating myocardium (HM), electron microscopy demonstrates mitochondrial dysregulation associated with hibernation (C,D) and significant recovery following CABG and stem cell treatment (E). * p < 0.05; *** p < 0.001
