Table 1.

Overview of in vivo studies investigating PGC1-alpha enhancing interventions.

Type	Intervention	Model	Sample	Biopsied Tissue	Reference
Lifestyle-based	Exercise	Human	n = 7	Skeletal Muscle	[78]
Dietary	CoQ10	Swine	n = 12	Myocardium	[75]
Pharmacological	Pioglitazone	Swine	n = 18	Myocardium	[74]
Cell-therapeutic	Mesenchymal Stem Cells	Swine	n = 12	Myocardium	[79]

Note: All studies found significantly increased PGC1-alpha expression with p-values < 0.05.