TABLE 2.
Effects of varying concentrations (3.1 to 12.5 μM) of 1-hp on the efflux of 45Ca2+ from FMLP-activated neutrophilsa
| System | Amt of 45Ca2+ released from neutrophils 60 s after addition of FMLP (pmol/107 cells) |
|---|---|
| FMLP only | 155 ± 10 |
| FMLP + 3.1 μM 1-hp | 145 ± 5 |
| FMLP + 6.25 μM 1-hp | 120 ± 5b |
| FMLP + 12.5 μM 1-hp | 95 ± 5b |
The results of six experiments are expressed as the mean values ± SEM.
P < 0.02 to 0.0001 for comparison with the 1-hp-free control system.