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. 2022 Nov 5;11(11):2190. doi: 10.3390/antiox11112190

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effect of bee bread on (A) Keap1 and (B) Nrf2 immunohistochemical expressions in liver sections of rats in all experimental groups. (C) Immunohistochemical analyses of Keap1 and (D) cytoplasmic and nuclear Nrf2 in liver sections. Magnification ×400, scale bars represent 20 μm. Values are presented as mean ± SEM, n = 6/group. CON, control; OB, obese; OB + BB, obese + bee bread 0.5 g/kg body weight/day; OB + OR, obese + orlistat 10 mg/kg body weight/day; Keap1, Kelch-like ECH-associated protein 1; Nrf2, nuclear factor erythroid 2-related factor 2. One-way ANOVA, followed by Tukey post-hoc test. ^a p < 0.05 vs. CON group, ^b p < 0.05 vs. OB group.