Table 5.
Expression as mean with standard deviation (SD), absolute reduction and percentage as well as p-value of the terminal ileum in the Crohn’s disease group (CD) separated by age group compared to age matched controls (C). Pediatric (P); adult (A), cystathionine-γ-lyase (CSE), 3-mercapto-sulfurtransferase (3-MST), ethylmalonic encephalopathy 1 protein (ETHE1), sulfide:quinone oxidoreductase (SQOR) and thiosulfate sulfurtransferase (TST). * = p-value < 0.05.
| CD—Terminal Ileum | 3-MST | CSE | ETHE1 | SQOR | TST |
|---|---|---|---|---|---|
| Expression Level, Mean (SD) | |||||
| CDA | 65 (53) | 35 (32) | 127 (82) | 42 (46) | 126 (77) |
| CA | 119 (96) | 42 (45) | 145 (89) | 38 (36) | 191 (92) |
| Reduction CA − CDA | 54 (46%) | 7 (17%) | 18 (12%) | −4 (−11%) | 65 (34%) |
| p-valueA | 0.139 | 0.5036 | 0.8129 | 0.9343 | 0.2533 |
| CDP | 154 (88) | 49 (35) | 236 (75) | 92 (96) | 184 (99) |
| CP | 165 (85) | 110 (53) | 228 (95) | 53 (37) | 237 (73) |
| Reduction CP − CDP | 11 (7%) | 61 (56%) | −8 (−4%) | −39 (−74%) | 53 (22%) |
| p-valueP | 0.8985 | 0.0396 * | 0.8132 | 0.6544 | 0.3759 |