Table 8.
Expression as mean with standard deviation (SD), absolute reduction and percentage as well as p-value of the ascending colon in children with Crohn’s disease (CDP) and children with ulcerative colitis (UCP) compared to age matched controls (CP). Pediatric (P); adult (A); cystathionine-γ-lyase (CSE); 3-mercapto-sulfurtransferase (3-MST); ethylmalonic encephalopathy 1 protein (ETHE1); sulfide:quinone oxidoreductase (SQOR) and thiosulfate sulfurtransferase (TST). * = p-value < 0.05, ** = p-value < 0.01.
| Ascending Colon | 3-MST | CSE | ETHE1 | SQOR | TST |
|---|---|---|---|---|---|
| Expression Level, Mean (SD) | |||||
| CDP | 178 (72) | 84 (44) | 228 (54) | 148 (75) | 231 (28) |
| CP | 210 (46) | 75 (46) | 262 (44) | 164 (56) | 258 (37) |
| Reduction CP − CDP | 32 (15%) | −9 (−12%) | 34 (13%) | 16 (10%) | 27 (10%) |
| p-value | 0.4635 | 0.5216 | 0.0837 | 0.5356 | 0.0308* |
| UCP | 197 (87) | 75 (65) | 239 (57) | 95 (55) | 202 (54) |
| CP | 210 (46) | 75 (46) | 262 (44) | 164 (56) | 258 (37) |
| Reduction Cp − UCP | 13 (6%) | 0 (0%) | 23 (9%) | 69 (42%) | 56 (22%) |
| p-value | 0.8514 | 0.7052 | 0.3238 | 0.0078 ** | 0.0118 * |