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. 2022 Nov 15;11(11):1628. doi: 10.3390/antibiotics11111628

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Scheme 1 — In vitro activity of naringenin and its derivatives against Gram-positive bacteria. (a) 1—7-O-methylnaringenin; 2—7-O-methylnaringenin oxime; 3—7,4′-di-O-methylnaringenin; 4—7,4′-di-O-methylnaringenin oxime; 5—7-O-ethylnaringenin; 6—7-O-ethylnaringenin oxime; 7—7-O-isopropylnaringenin; 8—7-O-isopropylnaringenin oxime; 9—7,4′-di-O-isopropylnaringenin; 10—7,4′-di-O-isopropylnaringenin oxime; 11—7-O-butylnaringenin; 12—7-O-butylnaringenin oxime; 13—7-O-pentylnaringenin; 14—7-O-pentylnaringenin oxime; 15—7-O-hexylnaringenin; 16—7-O-hexylnaringenin oxime; 17—7,4′-di-O-hexylnaringenin; 18—7,4′-di-O-hexylnaringenin oxime (based on Duda-Madej et al. [67]). (b) NG—naringenin; 19—6-fluoronaringenin; 20—6-chloronaringenin; 21—6-iodonaringenin; 22—6,8-difluoronaringenin; 23—6,8-dichloronaringenin; 24—6,8-diiodonaringenin (based on Mohammed et al. [68]).