Table 2.

There was vomiting and diarrhea in female dogs with mammary carcinoma after each chemotherapy (CT) session, according to the chemotherapy protocol. The numbers describe the number of vomiting and diarrhea events that each animal experienced from each group presented after 21 days of each chemotherapy session in carboplatin and carboplatin + cyclophosphamide treatment groups. Other adverse clinical events that have been described by the VCOG classification [15] were not significantly evident in these animals.

	Carboplatin (G1)						Carboplatin + Cyclophosphamide (G2)
Case Nº	1st CT	2nd CT	3rd CT	4th CT	5th CT	6th CT	1st CT	2nd CT	3rd CT	4th CT	5th CT	6th CT
	Vomiting
1	0	0	0	0	0	0	0	0	0	0	0	1
2	0	0	0	0	0	0	0	3	0	0	3	3
3	0	0	0	3	3	3	0	0	0	0	1	1
4	0	0	0	0	0	0	0	3	3	11	5	4
5	0	0	0	0	0	0	0	0	0	0	0	1
6	0	0	0	0	0	0	0	3	3	11	4	3
7	0	0	0	0	0	0	0	0	0	0	1	0
8	0	3	0	11	3	3	0	0	0	0	3	3
	Diarrhea
1	0	0	0	0	0	0	0	0	0	2	0	0
2	0	0	0	0	0	0	0	0	0	0	0	0
3	0	0	0	0	0	0	0	0	0	0	0	0
4	0	0	0	0	0	0	0	0	0	0	0	0
5	0	0	0	0	0	0	0	0	0	0	0	0
6	0	0	0	0	0	0	0	0	0	0	0	0
7	0	0	0	0	0	0	0	0	0	0	1	0
8	0	0	0	0	0	0	0	0	0	0	0	0