Table 1.
Effect of quercetin (QTN) oral dosing on body weight change, gonadosomatic index, and sperm characteristics of adult male Sprague Dawley rats exposed to aluminum trioxide nanoparticles (Al2O3NPs) and/or lead acetate (Pb Ac) for 60 days.
| Estimated Parameters | Experimental Groups | ||||||
|---|---|---|---|---|---|---|---|
| Control | CO | QTN | Al2O3NPs | Pb Ac | Al2O3NPs + Pb Ac | Al2O3NPs + Pb Ac + QTN | |
| Initial Body weight (g) | 182.00 ± 0.71 | 181.33 ± 3.79 | 182.00 ± 2.55 | 186.67 ± 3.70 | 185.33 ± 1.89 | 188.33 ± 3.01 | 189.33 ± 2.05 |
| Final body weight (g) | 250.67 b ± 10.02 | 245.00 b ± 14.71 | 273.33 a ± 15.74 | 231.67 bc ± 1.65 | 202.33 c ± 7.10 | 208.00 c ± 8.64 | 270.67 a ± 14.27 |
| Body weight change (g) | 68.67 ab ± 10.73 | 63.00 ab ± 12.90 | 86.67 a ± 16.41 | 45.00 bc ± 2.94 | 17.00 c ± 6.75 | 19.67 c ± 7.55 | 81.33 a ± 14.06 |
| Testes weight (g) | 2.03 a ± 0.08 | 1.92 a ± 0.07 | 2.19 a ± 0.02 | 1.40 b ± 0.12 | 1.20 b ± 0.11 | 1.10 b ± 0.11 | 2.15 a ± 0.20 |
| Gonadosomatic index (%) | 0.82 a ± 0.05 | 0.80 a ± 0.08 | 0.81 a ± 0.05 | 0.61 b ± 0.06 | 0.60 b ± 0.07 | 0.52 b ± 0.03 | 0.80 a ± 0.07 |
| Sperm count (sp.cc/mL × 125 × 104) | 75.00 ± 3.46 bc | 76.00 b ± 1.53 | 82.00 a ± 2.08 | 61.67 d ± 1.20 | 54.33 e ± 0.88 | 40.3 f ± 0.88 | 69.67 c ± 1.76 |
| Sperm abnormalities (%) | 16.66 d ± 1.09 | 17.50 d ± 0.58 | 13.16 d ± 1.59 | 40.50 b ± 2.08 | 43.33 ab ± 2.40 | 50.00 a ± 5.20 | 32.50 c ± 1.60 |
| Sperm motility (%) | 88.67 b ± 0.88 | 85.33 b ± 0.33 | 94.33 a ± 1.20 | 50.00 d ± 2.89 | 33.33 e ± 1.67 | 16.67 f ± 0.88 | 63.33 c ± 1.67 |
Means within the same row carrying different superscripts (a, b, c, d, e, and f) are significantly different at p < 0.05. The values shown are means ± SE. n = 10.