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. 2022 Nov 8;11(11):2211. doi: 10.3390/antiox11112211

Table 3.

Shows the device description and LED dosimetry and treatment protocols for sublingual photobiomodulation therapy.

Type of Device Semi-Circular Non-Thermal LED Device
Light source Light Emitting Diodes
Beam type Non-Coherent
Wavelength 660 nm
Operation emission mode Continuous mode
Number of LEDs 6
Irradiance per each LED 5.5 mW/cm2
Spot size per LED 0.045 cm2
Power output per each LED 122 mW
Total power output 732 mW
Device aperture (over sublingual vein) 9 cm2
Total power density (irradiance) 81 mW/cm2
Total treatment duration 5 min (300 s)
Estimated blood exposure 60 s
Energy density (blood) 4.9 J/cm2
Treatment interval Variable: between 8–24 h (hours)