Table 4.

Evolution of COVID-19 Treatment Protocol from August 2020 to July 2021.

Intervention	August 2020–March 2021	June/July 2021 (Pilot Study)	LUMINNOVA Upper Respiratory Protocol
Oral MB	Optional: used if symptoms were severe/delayed presentation	Initially 1 mg/kg administered 12-hourly.	Up to 2 mg/kg administered 8-hourly for a total of 8 treatments (unless contraindicated or very mild presentation).
Sublingual PBM	Not utilized	Initially utilized for a patient that had not adequately responded to oral MB and in a case where oral MB was contraindicated.	Administered eight treatments every 8 h or until symptoms were resolved
Oral/nasal PDT	Total of two treatment sessions 12 h apart.	The number of treatment sessions gradually evolved as we observed the changes in CT values each day.	Treatment course consisted of eight sessions carried out every 8 h.