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. 2022 Oct 31;149(21):dev200909. doi: 10.1242/dev.200909

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© 2022. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 2. — Sequencing of Cxcl12⁺ cells uncovers heterogeneity and previously undefined arterial EC subpopulations. (A) FACS strategy and plots for Cxcl12-DsRed⁺ cells. (B) UMAP embedding of Cxcl12-DsRed⁺ cells (n=26,652) colored by cell type. (C) Dot plot of marker genes for each cell type where dot size indicates the proportion of cells within a cluster expressing a gene, and color intensity indicates the relative expression level. (D) UMAP embedding colored by time point. (E) Cellular composition changes in Cxcl12⁺ ECs over time.