CAVD	Calcific aortic valve disease
NRVD	Nonrheumatic valve disease
VICs	Valve interstitial cells
ROS	Reactive oxygen species
OS	Oxidative stress
Nrf2	Nuclear factor erythroid 2-related factor 2
ARE	Antioxidant response element
NQO1	NAD(P)H-quinone oxidoreductase 1
HO-1	Heme oxygenase-1
VSMCs	Vascular smooth muscle cells
LPS	Lipopolysaccharide
Sirt7	Sirtuin 7
CVDs	Cardiovascular diseases
DWI	Direct wire injury
CCK8	Cell Counter Kit 8
AVA	Aortic valve area
HE	Hematoxylin and eosin
TCMSP	Traditional Chinese Medicine Systems Pharmacology
NLM	National Library of Medicine
KEGG	Kyoto Encyclopedia of Genes and Genomes
MCMP	Mitochondrial membrane potential
TMRM	Tetramethylrhodamine
NAC	N-acetyl-L-cysteine
Runx2	Runt-related transcription factor 2