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. 2022 Nov 7;11(11):1626. doi: 10.3390/biology11111626

Table 1.

Suspected Infection Variables and definition of sepsis and septic shock.

GENERAL VARIABLES CUT-OFF
Fever >38.3 °C
Hypotermia <36 °C
Heart Rate >90 min or more than two S.D. above the normal value for age
Tachypnea >20 rr/min
Altered Mental Status impairment
Significant Edema or positive fluid balance >20 ml/kg over 24 h
Hyperglycemia pGluc > 140 mg/dl in the absence of diabetes
INFLAMMATORY VARIABLES CUT-OFF
Leukocytosis WBC count > 12,000/µL
Leukopenia WBC count < 12,000/µL
DISEASE DEFINITION (SEPSIS-3)
Sepsis Suspected/confirmed infection+≥2 criteria of SOFA
Septic Shock Sepsis+ fluid refractory Hypotension_
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    Lactate 2 mmol/l

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    Vasopressor for MAP ≥ 60 mmHg