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. 2022 Nov 10;13:1041789. doi: 10.3389/fmicb.2022.1041789

Table 3.

Clinical manifestations of C. trachomatis-infected women with respect to age, clinical departments, antibiotic usage and HPV infection.

Manifestations Age (year) pa value Clinical departmentsb p value Antibiotic usage (previous 3 months) p value HPV infection p value
≤25 n = 63 25–35 n = 140 35–45 n = 58 >45 n = 42 PEC n = 80 ART n = 59 GC n = 164 Yes n = 14 No n = 289 Yes n = 71 No n = 232
Asymptomatic (%)
Yes 20.6 27.9 32.8 40.5 0.15 71.3 23.7 10.4 <0.001 7.1 30.1 0.122 16.9 32.8 0.01
No 79.4 72.1 67.2 59.5 28.8 76.3 89.6 92.9 69.9 83.1 67.2
Vaginosis (%)
Yes 52.4 39.3 29.3 28.6 0.03 16.3 32.2 51.8 <0.001 57.1 37.7 0.145 45.1 36.6 0.202
No 47.6 60.7 70.7 71.4 83.8 67.8 48.2 42.9 62.3 54.9 63.4
Pelvic inflammatory disease (%)
Yes 6.3 14.3 17.2 0.0 0.017 0.0 33.9 8.5 <0.001 42.9 9.7 0.001 8.5 12.1 0.398
No 93.7 85.7 82.8 100.0 100.0 66.1 91.5 57.1 90.3 91.5 87.9
Cervicitis (%)
Yes 6.3 7.9 10.3 11.9 0.726 12.5 10.2 6.1 0.218 0.0 9.0 0.493 8.5 8.6 0.964
No 93.7 92.1 89.7 88.1 87.5 89.8 93.9 100.0 91.0 91.5 91.4
Vagina cleanliness (%)
I/II 31.6 35.3 41.7 40.6 0.97 46.8 44.8 18.3 <0.001 41.7 36.2 0.671 34.6 37.2 0.439
III 36.8 37.3 33.3 31.3 40.5 34.5 31.0 41.7 35.2 30.8 37.2
IV 31.6 27.5 25.0 28.1 12.7 20.7 50.7 16.7 28.6 34.6 25.6
Cervical abnormalities (%)c
Benign 76.6 82.8 83.3 86.1 0.792 88.6 83.9 78.1 0.371 87.5 82.0 0.78 62.7 88.3 <0.001
ASC-US 10.6 5.2 4.2 2.8 2.5 6.5 7.3 0.0 5.9 13.6 3.2
SIL 12.8 12.1 12.5 11.1 8.9 9.7 14.6 12.5 12.1 23.7 8.5

ap values were calculated using Chi-square tests. Bold p value indicate statistically significant, i.e., p < 0.05.bPEC, physical examination center; ART, assisted reproductive technology; GC, gynecology clinics.cASC-US, atypical squamous cells of undetermined significance; SIL, squamous intraepithelial lesion.