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. 2022 Nov 22;99(21):e2395–e2405. doi: 10.1212/WNL.0000000000201200

Figure 5. Multilinear Model With k-Fold Cross-validation in the Delta Frequency Band.

Figure 5

Using as predictors age, education, sex, disease duration, ALS phenotype, ECAS, and the size of the functional repertoire, the model predicts (A and B) the ALSFRS-R (age: p = 0.038, β = −0.23; disease duration: p = 0.020, β = −0.05; functional repertoire: p < 0.001, β = 0.11); (C and D) the King's clinical staging system (disease duration: p < 0.01, β = 0.01; functional repertoire: p < 0.001, β = −0.02). In (A and C), the explained variance of the variable to be predicted as a function of the predictors is illustrated. Significant predictors are indicated by asterisks; positive and negative coefficients are illustrated with β+ and β−, respectively; significance p-values: *p < 0.05, **p < 0.01, ***p < 0.001. In (B and D), scatter plots of the comparison between actual and predicted values are reported. The figure was made using Matlab 2019a. ALS = myotrophic lateral sclerosis; ECAS = Edinburgh Cognitive and Behavioural ALS Screen