Table 2.
Semiquantitative evaluation—histology sections of liver, spleen, kidney, and abdominal wall for immune cell presence and fibrosis.
Organ | Parameter | CHX | Control | ||
---|---|---|---|---|---|
1 Week | 3 Weeks | 1 Week | 3 Weeks | ||
liver | lymphocytes | ++ | +/++ | - | - |
neutrophils | ++ | +/++ | - | - | |
fibrosis | + | ++ | - | - | |
spleen | lymphocytes | -/+ | -/+ | - | -/+ |
neutrophils | + | ++ | -/+ | -/+ | |
capsule | + | + | -/+ | + | |
kidney | PMN/MNC | -/+ | -/+ | - | - |
fibrosis | -/+ | -/+ | - | - | |
Abd. wall peritoneum |
PMNs | +/++ | +/++ | - | - |
MNCs | + | -/+ | - | - | |
edema | +/++ | +++ | - | - | |
fibroblasts | + | ++ | - | - | |
Abd. wall injury |
depth | up to 25% | up to 25% | - | - |
No change (-), scarce (-/+), mild (+), moderate (++), severe (+++). CHX: chlorhexidine gluconate, PMNs: polymorphonuclear cells, MNCs: mononuclear cells.