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. 2022 Oct 25;12(11):1557. doi: 10.3390/biom12111557
IGF-1 Insulin-like growth factor 1
IGF-2 Insulin-like growth factor 2
ECM Extracellular matrix
IR Insulin receptor
IGF-1R Insulin-like growth factor receptor 1
IGF-2R Insulin-like growth factor receptor 2
DMRs Differentially methylated regions
ICR Imprinting control region
CTCF CCCTC-binding factor
BWS Beckwith–Wiedemann Syndrome
RSS Russell–Silver syndrome
CI-MPR Cation-independent mannose-6-phosphate receptor
CD-MPR Cation-dependent mannose-6-phosphate receptor
GSK3 Glycogen synthase kinase 3
MAPK Mitogen-activated protein kinase
PI3K Phosphatidylinositol-3-kinase
Akt Protein kinase B
IRS Insulin receptor substrates
mTOR Mammalian target of rapamycin
ERK Extracellular-regulated protein kinase
c-fos Fos proto-oncogene, AP-1 transcription factor subunit
c-jun Jun proto-oncogene, AP-1 transcription factor subunit
EGFR Epidermal growth factor receptor
HER2 (ERB2) Erb-b2 receptor tyrosine kinase 2
HER (ERBB3) Erb-b2 receptor tyrosine kinase 3
SSc Systemic sclerosis
IPF Idiopathic pulmonary fibrosis
JNK (MAPK8) Mitogen-activated protein kinase 8
AP-1 Activator protein 1
ATF-2 Activating transcription factor 2
MMP Matrix metalloproteinase
Ang II Angiotensin II
TIMP Tissue inhibitor of metalloprotease
Gaq (GNAQ) G protein subunit alpha q
PLC-β Phospholipase C beta
PA Plasminogen activator
CaMKIIδ Calcium/calmodulin-dependent protein kinase II
HSC Hepatic stellate cell
CCl4 Carbon tetrachloride
2-FAA 2-fluorenylacetamide
α-SMA α-smooth muscle actin
CKD Chronic kidney disease
CTGF Connective tissue growth factor
BMP Bone morphogenetic protein
PDGF Platelet-derived growth factor
OSF Oral submucosal fibrosis